HDinHD: Open Source Science for the HD Research Community
The goal of HDinHD is to foster and support a collaborative community united in its drive to accelerate the development of therapeutics that will delay the onset and/or ameliorate the effects of Huntington’s disease. HDinHD seeks to achieve this through:
- Sharing HD-related primary scientific data
- Sharing analyses and computational models built from HD-related scientific data
- Providing browsing and data interrogation tools over both primary and analyzed data that facilitate data exploration and hypothesis generation
- Building a forum for HD researchers to highlight their data, tools, know-how and insight to the community
The HDinHD website is currently a joint development effort by CHDI and UCLA, through the laboratory of Dr. Giovanni Coppola. As you will see when you Register for access, HDinHD highlights data and tools provided by the broader community. If you are interested in Contributing Data to HDinHD, suggest links to other HD-related scientific data or websites, or would otherwise like to provide Feedback to us, we encourage you to do so. HDinHD is for the community; please help us tailor and grow HDinHD in a direction that can make a difference to your research, and ultimately, to improve the lives of HD families.
Want to learn more about HDinHD?
Watch a detailed video overview of HDinHD presented at the 16th Annual HD Therapeutics Conference (April 2021). The video outlines data resources and tools within HDinHD and provides a detailed demonstration of the new HD Explorer tool. |
Read the following publication introducing HDinHD: HDinHD: A Rich Data Portal for Huntington’s Disease Research, J Huntingtons Dis., 10, 405-412
Latest news and publications from around the HD Ecosystem
HDBuzz
- March 2025: This Month in Huntington’s Disease Research
- Molecular Surgeons for Huntington’s Disease Catch a RIDE with CRISPR Advancements
- Huntington’s Disease Heroes: A Gratitude Day Feature on Factor-H
- This Gratitude Day, HDBuzz Is Grateful For The Partnership Between HD Families And Scientists
- The Huntington’s Disease Youth Organization’s World Congress: Supporting Young People Affected by HD
Literature
- Progressively reduced cerebral oxygen metabolism and elevated plasma NfL levels in the zQ175DN mouse model of Huntington's disease
- Interrogating DNA methylation associated with Lewy body pathology in a cross brain-region and multi-cohort study
- Uncovering synaptic and cellular nanoarchitecture of brain tissue via seamless <em>in situ</em> trimming and milling for cryo-electron tomography
- Emerging roles of microglia and neuroinflammation in Huntington's disease: From pathophysiology to clinical trials
- 1953-2023. Seventy Years of the Nerve Growth Factor: A Potential Novel Treatment in Neurological Diseases?
News
- Have We Been Thinking About the Causes of Huntington Disease All Wrong?
- Delicate balancing act determines how many genome gateways form in cells | ScienceDaily
- Area elementary schoolers to compete in 'Odyssey of the Mind' World Finals - WQOW
- Emerging roles of microglia and neuroinflammation in Huntington's disease - ResearchGate
- Wave Life Sciences' SWOT analysis: RNA editing pioneer faces challenges in genetic medicine stock